Bachelor of Pharmacy

Bachelor of Pharmacy ( B Pharm)

Bachelor of Pharmacy (B Pharma) Course offered by MVM College of Pharmacy is Recognized by Pharmacy Council of India, All India Council of Technical Educations , Affiliated to Rajiv Gandhi University of Health Sciences Karnataka, and recognized by Government of Karnataka

Commencement of session : August

Course Duration

4 years + practical training of 500 hours spread over a period of not less than 3 months in a Government Hospital or Pharmacy, which is recognized by Pharmacy Council of India, New Delhi.

Eligibility

Candidates should have passed 10+2 examination with Physics and Chemistry as compulsory subjects along with one of the following – Mathematics / Computer Science / Biotechnology / Biology. Obtained at least 40% marks (35% in case of candidate belonging to reserved category) in the above subjects taken together.

Candidates who have passed D.Pharm course approved by Pharmacy Council of India shall also be eligible to this course and can be admitted directly to the 2nd Year.

Age

17 years and above ( Only those whose date of birth falls on or before 31.12.2002 are eligible)

Attendance Requirement

A minimum of 80% in both theory and practical (regular) class is essential to get eligibility for sessional as well as semester exam.

Industrial Tour & Training

Every candidate shall undergo practical training in Pharmaceutical Manufacturing House / Approved Hospital / CSIR research labs for a period of not less than one hundred and fifty hours to be covered in not less than 45 days after completing 3rd year or 4th year. Candidate should submit two copies of the training report duly certificated by the authorities of the training center in which he/she has undergone training, duly accepted and certified by the Head of the Department. Candidates studying in final year of the course shall visit several pharmaceutical manufacturing houses as a supplement to their academic training and submit a report to the satisfaction of the Head of Department where he / she has studied.

Internal Assessment Marks

During each academic year three sets of exams for theory paper will be conducted for maximum marks of 30 and an average of best two exams will be considered. For practical papers internal assessment marks for maximum marks of 30 will be awarded considering the student’s regularity, manipulative skill, and viva voice during regular practical classes.

Syllabus

Semester – 1

Semester – 2

Semester – 3

Semester – 4

Semester – 5

Semester – 6

Semester – 7

Semester – 8

Human Anatomy and Physiology – 1
- Introduction to HAP
- Cellular level of organization
- Tissue level of organization
- Integumentary system
- Musculoskeletal system
- Joints
- Body fluids, Blood
- Lymphatic system
- Peripheral nervous system
- Special senses
- Cardiovascular system
Pharmaceutical Analysis – 1
- Pharmaceutical analysis –Introduction
- Errors
- Pharmacopoeia
- Acid-base titration
- Non-aqueous titration
- Precipitation titrations
- Complexometric titrations
- Gravimetry
- Diazotization Titrations
- Redox Titrations
- Electrochemical methods of Analysis
Pharmaceutics – 1
- Historical Background and development of the profession of pharmacy
- Dosage Forms
- Prescription
- Posology
- Pharmaceutical calculations
- Powders
- Liquid dosage forms
- Monophasic liquids
- Biphasic Liquids
- Emulsions
- Suppositories
- Pharmaceutical Incompatibilities
- Semisolid Dosage Forms
Pharmaceutical Inorganic Chemistry
- Impurities in pharmaceutical substances
- Acids, Bases and Buffers
- Major extra and intracellular electrolytes
- Dental products
- Gastrointestinal agents
- Miscellaneous compounds
- Radiopharmaceuticals

Human Anatomy and Physiology – 2
- Nervous System
- Digestive System
- Energetics
- Respiratory System
- Urinary System
- Endocrine System
- Reproductive System
- Introduction to Genetics
Biochemistry
- Biomolecules
- Bioenergetics
- Carbohydrate metabolism
- Biological oxidation
- Lipid metabolism
- Amino acid metabolism
- Nucleic acid metabolism and genetic information transfer
- Enzymes
Pathophysiology
- Basic principles of Cell injury and Adaptation
- Basic mechanism involved in the process of inflammation and repair
- Cardiovascular System:
- Respiratory system
- Renal system
- Haematological Diseases
- Endocrine system:
- Nervous system
- Gastrointestinal system:
- Disease of bones and joints
- Principles of cancer
- Infectious diseases
- Sexually transmitted diseases
Pharmaceutical Organic Chemistry – 1
- Classification, nomenclature and isomerism
- Alkanes, Alkenes and Conjugated dienes
- Alkyl halides
- Alcohols
- Carbonyl compounds (Aldehydes and ketones)
- Carboxylic acids
- Aliphatic amines

Pharmaceutical Organic Chemistry – 2
- Benzene and its derivatives
- Phenols
- Aromatic Amines
- Aromatic Acids
- Fats and Oils
- Polynuclear hydrocarbons
- Cyclo alkanes
Pharmaceutical Microbiology
- Introduction to Microbiology
- Study of cell culture
- Cultivation of Aerobes, Anaerobes
- Instrumentation
- Staining Techniques
- Sterilization Techniques
- Study of Fungi & Viruses
- Study of Disinfectants
- Study of Bacteriostatic & Bactericidal
- Sterility Techniques
- Aseptic Area
- Microbiological Assay
- Evaluation of Microbial Stability
- Culture Techniques
- Application of cell culture
Physical Pharmaceutics – 1
- Solubility
- States of matter and properties of matter
- Physicochemical properties of drug molecules
- Surface and interfacial phenomenon
- Complexation and Protein Binding
- pH buffers and Isotonic Solutions
Pharmaceutical Engineering
- Flow of fluids
- Size Reduction
- Size Separation
- Heat Transfer
- Evaporation
- Distillation
- Drying
- Mixing
- Filtration
- Centrifugation
- Materials of pharmaceutical plant construction, Corrosion and its prevention

Pharmaceutical Organic Chemistry – 3
- Stereo isomerism
- Geometrical isomerism
- Heterocyclic compounds
- Synthesis and Reactions
- Reactions of synthetic importance
Medicinal Chemistry – 1
- Physicochemical properties in relation to biological action
- Drug metabolism
- Drugs acting on Autonomic Nervous System
- Adrenergic Neurotransmitters
- Sympathomimetic agents: SAR of Sympathomimetic agents
- Adrenergic Antagonists
- Cholinergic neurotransmitters
- Parasympathomimetic agents
- Direct acting agents
- Indirect acting/ Cholinesterase inhibitors (Reversible & Irreversible)
- Cholinesterase reactivator
- Cholinergic Blocking agents
- Solanaceous alkaloids and analogues
- Synthetic cholinergic blocking agents
- Drugs acting on Central Nervous System
- Sedatives and Hypnotics
- Antipsychotics
- Anticonvulsants
- General anaesthetics
- Narcotic and non-narcotic analgesics
Physical Pharmaceutics – 2
- Colloidal dispersions
- Rheology
- Deformation of solids
- Coarse dispersion
- Micromeretic
- Drug stability
Pharmacology – 1
- General Pharmacology
- Pharmacology of drugs acting on the peripheral nervous system
- Pharmacology of drugs acting on the central nervous system
Pharmacognosy & Pytochemistry – 1
- Introduction to Pharmacognosy
- Classification of drugs
- Quality control of Drugs of Natural Origin
- Cultivation, Collection, Processing and storage of drugs of natural origin
- Conservation of medicinal plants
- Plant tissue culture
- Pharmacognosy in various systems of medicine
- Introduction to secondary metabolites
- Plant Products
- Primary metabolites
- Carbohydrates
- Proteins and Enzymes
- Lipids(Waxes, fats, fixed oils)
- Marine Drugs

Medicinal Chemistry – 2
- Antihistaminic agents
- H1 – antagonists
- H2 – antagonists
- Gastric Proton pump inhibitors
- Anti-neoplastic agents
- Anti-anginal
- Diuretics
- Anti-hypertensive Agents
- Anti-arrhythmic Drugs
- Anti-hyperlipidemic agents
- Coagulant & Anticoagulants
- Drugs used in Congestive Heart Failure
- Drugs acting on Endocrine system
- Sex hormones
- Drugs for erectile dysfunction
- Oral contraceptives
- Corticosteroids
- Thyroid and antithyroid drugs
- Antidiabetic agents
- Local Anaesthetics
- Benzoic Acid derivatives
- Amino Benzoic acid derivatives
- Lidocaine/Anilide derivatives
- Miscellaneous
Industrial Pharmacy – 1
- Preformulation Studies
- Physical properties
- Chemical Properties
- Tablets
- Liquid orals
- Capsules
- Parenteral Products
- Ophthalmic Preparations
- Cosmetics
- Pharmaceutical Aerosols
- Packaging Materials Science
Pharmacology – 2
- Pharmacology of drugs acting on cardio vascular system
- Pharmacology of drugs acting on urinary system
- Autacoids and related drugs
- Pharmacology of drugs acting on endocrine system
- Bioassay
Pharmacognosy and Phytochemistry – 2
- Metabolic pathways in higher plants and their determination
- General introduction of Secondary Metabolities
- Isolation,Identification and Analysis of Phytoconstituents
- Phytoconstituents
- Basics of Phytochemistry
Pharmaceutical Jurisprudence
- Drugs and Cosmetics Act, 1940 and its rules 1945
- Pharmacy Act – 1948
- Medicinal and Toilet Preparation Act –1955
- Narcotic Drugs and Psychotropic substances Act-1985 and Rules
- Study of Salient Features of Drugs and Magic Remedies Act and its rules
- Prevention of Cruelty to animals Act-1960
- National Pharmaceutical Pricing Authority
- Pharmaceutical Legislations
- Code of Pharmaceutical ethics
- Medical Termination of Pregnancy Act
- Right to Information Act
- Introduction to Intellectual Property Rights (IPR)

Medicinal Chemistry – 3
- Antibiotics
- β-Lactam antibiotics
- Aminoglycosides
- Tetracyclines
- Macrolide
- Miscellaneous
- Prodrugs
- Antimalarials
- Quinolines
- Biguanides and dihydro triazines
- Miscellaneous
- Anti-tubercular Agents
- Urinary tract anti-infective agents
- Antiviral agents
- Antifungal agents
- Introduction to Drug Design
- Combinatorial Chemistry
Pharmacology – 3
- Pharmacology of drugs acting on Respiratory system
- Chemotherapy
- Immunopharmacology
- Principles of toxicology
- Chronopharmacology
Herbal Drug Technology
- Herbs as raw materials
- Biodynamic Agriculture
- Indian Systems of Medicine
- Nutraceuticals
- Herbal-Drug and Herb-Food Interactions
- Herbal Cosmetics
- Herbal excipients
- Herbal formulations
- Evaluation of Drugs
- Patenting and Regulatory requirements of natural products:
- Regulatory Issues
- General Introduction to Herbal Industry
- Schedule T – Good Manufacturing Practice of Indian systems of medicine
Biopharmaceutics and Pharmacokinetics
- Introduction to Bio-Pharmaceutics
- Elimination
- Bioavailability and Bioequivalence
- Pharmacokinetics
- Multicompartment models
- Nonlinear Pharmacokinetics
Pharmaceutical Biotechnology
- Brief introduction to Biotechnology
- Enzyme Biotechnology
- Biosensors
- Microbes
- Genetic engineering
- Immunity
- Bacterial vaccines
- Hybridoma technology
- Immuno blotting techniques
- Genetic organization
- Microbial genetics
- Mutation
- Fermentation methods
- Production of drugs
- Blood Products
Quality Assurance
- Quality Assurance and Quality Management concepts
- Total Quality Management (TQM)
- ICH guidelines
- Quality by design (QbD)
- ISO 9000 & ISO14000
- NABL accreditation
- Organization and personnel
- Premises
- Equipment and raw materials
- Quality Control
- Good Laboratory Practice
- Complaints
- Documents maintenance in Pharmaceutical Industry
- Calibration and Validation
- Warehousing

Instrumental Methods of Analysis
- UV Visible spectroscopy
- Fluorimetry
- IR spectroscopy
- Flame Photometry
- Atomic absorption spectroscopy
- Nepheloturbidometry
- Adsorption and partition column chromatography
- Thin layer chromatography
- Paper chromatography
- Electrophoresis
- Gas chromatography
- High performance liquid chromatography (HPLC)
- Ion exchange chromatography
- Gel chromatography-
- Affinity chromatography
Industrial Pharmacy – 2
- Pilot plant scale up techniques
- Technology development and transfer
- Regulatory affairs
- Quality management systems
- Indian Regulatory Requirements
Pharmacy Practice
- Hospital and it’s organization
- Hospital pharmacy and its organization
- Adverse drug reaction
- Community Pharmacy
- Drug distribution system in a hospital
- Hospital formulary
- Therapeutic drug monitoring
- Medication adherence
- Patient medication history interview
- Community pharmacy management
- Drug information services
- Patient counselling
- Education and training program in the hospital
- Prescribed medication order and communication skills
- Budget preparation and implementation
- Over the counter (OTC) sales
- Drug store management and inventory control
- Investigational use of drugs
- Interpretation of Clinical Laboratory Tests
Novel Drug Delivery
- Controlled drug delivery systems
- Polymers
- Microencapsulation
- Mucosal Drug Delivery system
- Implantable Drug Delivery Systems
- Transdermal Drug Delivery Systems
- Gastroretentive drug delivery systems
- Nasopulmonary drug delivery system
- Targeted drug Delivery
- Ocular Drug Delivery Systems
- Intrauterine Drug Delivery Systems

Biostatistics & Research Methodology
- Introduction
- Measures of central tendency
- Measures of dispersion
- Correlation
- Regression
- Probability
- Parametric test
- Non Parametric tests
- Introduction
- to Research
- Graphs
- Designing the methodology
- Regression modelling
- Introduction to Practical components of Industrial and Clinical Trials Problems:
- Factorial Design
- Response Surface methodology
Social and Preventive Pharmacy
- Concept of health and disease
- Social and health education
- Sociology and health
Pharma Marketing Management
- Hygiene and health
- Preventive medicine
- National health programs, its objectives, functioning and outcome of the following
- Health
- Community
Pharmaceutical Regulatory Science
- New Drug Discovery and development
- Regulatory Approval Process
- Regulatory authorities and agencies
- Registration of Indian drug product in overseas market
- Clinical trials
- Regulatory Concepts
Pharmacovigilance
- Introduction to Pharmacovigilance
- Drug and disease classification
- Drug dictionaries and coding in pharmacovigilance
- Information resources in pharmacovigilance
- Establishing pharmacovigilance programme
- Vaccine safety surveillance
- Pharmacovigilance methods
- Communication in pharmacovigilance
- Safety data generation
- ICH Guidelines for Pharmacovigilance
- Pharmacogenomics of adverse drug reactions
- Drug safety evaluation in special population
- CIOMS
- CDSCO (India) and Pharmacovigilance
Quality Control and Standardization of Herbals
- Basic tests for drugs
- Quality assurance in herbal drug industry
- Testing
- Regulatory Requirements
Computer Aided Drug Design
- Drug Discovery and Development
- Lead discovery and Analog Based Drug Design
- Analog Based Drug Design
- Quantitative Structure Activity Relationship (QSAR)
- Molecular Modeling and virtual screening techniques
- Molecular docking
- Informatics & Methods in drug design
- Molecular Modeling
Cell and Molecular Biology
- Cell and Molecular Biology: History and Summation.
- Properties of cells and cell membrane
- Prokaryotic versus Eukaryotic
- Cellular Reproduction
- Chemical Foundations – an Introduction and Reactions (Types)
- DNA and the Flow of Molecular Information
- DNA and RNA
- Types of RNA
- Transcription and Translation
- Proteins: Defined and Amino Acids
- Protein Structure
- Regularities in Protein Pathways
- Cellular Processes
- Positive Control and significance of Protein Synthesis
- Science of Genetics
- Transgenics and Genomic Analysis
- Cell Cycle analysis
- Mitosis and Meiosis
- Cellular Activities and Checkpoints
- Cell Signals: Introduction
- Receptors for Cell Signals
- Signaling Pathways: Overview
- Misregulation of Signaling Pathways
- Protein-Kinases
Experimental Pharmacology
- Laboratory Animals
- Pre-clinical screening models
- Study of screening animal models for
- Preclinical screening models
- Research methodology and Bio-statistics
Advanced Instrumentation Techniques
- Nuclear Magnetic Resonance spectroscopy
- Mass Spectrometry
- Thermal Methods of Analysis
- X-Ray Diffraction Methods
- Calibration and validation
- Radio immune assay
- Extraction techniques
- Hyphenated techniques
Cosmetic Science
- Introduction to Cosmetics
- Cosmetic excipients
- Skin
- Hair
- Oral Cavity
- Principles of formulation and building blocks of skin care products
- Role of herbs in cosmetics
- Analytical cosmetics
- Principles of Cosmetic Evaluation
- Oily and dry skin
- Cosmetic problems associated with Hair and scalp
- Cosmetic problems associated with skin
- Antiperspirants and Deodorants
Dietary Supplements and Nutraceuticals
- Disease prevent by nutraceuticals
- Medicinal uses and health benefits of nutraceuticals
- Chemical nature medicinal benefits
- Polyphenolics
- Flavonoids
- Free radicals
- Antioxidants
- Melatonin Synthetic antioxidants
- Regulatory Aspects
Elective course on Pharmaceutical Product Development
- Introduction to Pre-formulation Studies
- Study of Pharmaceutical Excipients
- Optimization Techniques